Additional Information for Suppository Base
Suppository bases are substances used to prepare suppositories, which are solid dosage forms that are inserted into the rectum or vagina for localized or systemic drug delivery. These bases provide a suitable matrix for the active pharmaceutical ingredient (API) and help in the controlled release of the drug.
In the supply class Drugs And Biologicals, suppository bases are categorized as pharmaceutical ingredients used in the formulation of medications. They are part of the supply group Medical, Dental, And Veterinary Equipment And Supplies, which includes various medical, dental, and veterinary products and equipment.
Suppository bases can be made from different materials, including:
1. Fatty Bases: These are typically made from a combination of fats and oils, such as cocoa butter, hydrogenated vegetable oils, and glycerides. Fatty bases are solid at room temperature but melt at body temperature, allowing for easy insertion and drug release.
2. Water-Soluble Bases: These bases are made from water-soluble polymers, such as polyethylene glycols (PEGs) or glycerinated gelatin. They dissolve in body fluids, releasing the drug for absorption.
3. Miscellaneous Bases: Other types of bases include mixtures of fatty and water-soluble bases, such as PEG and cocoa butter combinations.
The choice of suppository base depends on factors such as the drug's solubility, stability, and desired release profile. Different bases have different melting points, hardness, and drug release characteristics, allowing for customization based on the specific medication being formulated.
It's important to note that suppository bases are typically used by pharmaceutical manufacturers or compounding pharmacies to prepare suppositories. They are not standalone products but rather components used in the formulation of medications.
If you have any specific questions or need further information, feel free to ask!
Related Item Names for INC 46479 Suppository Base
NATO Stock Numbers with Item Name 46479 Suppository Base Page 1 of 1
- NDC00574-9100-01
- RNCC: 3 | RNVC: 2 | DAC: 4
- S 55
- RNCC: 5 | RNVC: 1 | DAC: 4